Suyanta, Siti Nur Akmar Mohd Yazid, Illyas Md Isa, Norhayati Hashim, Mohamad Syahrizal Ahmad
Recently, Fe3O4 nanostructures are studied extensively for the use of enzymatic glucose sensor applications. However, reports on the non-enzymatic sensing performance of Fe3O4 for direct oxidation of glucose are rare. Therefore, in this work, a novel glassy carbon electrode modified with iron oxide/graphene nanocomposites (Fe3O4/graphene/GCE) was used for the non-enzymatic amperometric determination of glucose. The Fe3O4/graphene nanocomposite was first synthesised in alkaline aqueous solution through a simple chemical reduction process. The modified electrode was then studied for a non-enzymatic glucose sensing application in 0.1 M KNO3 supporting electrolyte (pH = 3.0). Under optimized conditions, the low detection limit of 0.18 μM with a linear range from 50 μM to 4.00 mM as well as good sensitivity (959.00 μA mM-1 cm2), stability and reproducibility have been obtained using the Fe3O4/graphene/GCE, thus, leading to a promising candidate for non-enzymatic glucose detection. The sensor was employed for the testing of glucose concentration in real blood samples. © 2018 The Authors.
Deparment of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Yogyakarta, Indonesia; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, Tanjung Malim, Perak, 35900, Malaysia
