Mohamad Syahrizal Ahmad, Illyas Md Isa, Norhayati Hashim, Suyanta M. Si, Mohamad Idris Saidin
A new zinc-layered hydroxide-L-phenylalanate (ZLH-LP)-modified multiwalled carbon nanotube (MWCNT) was prepared as a new material of paste electrode for the detection of paracetamol (PCM) in 1.0 × 10−1 M phosphate buffer solution and at pH 7.5. The electrochemical characterization of the MWCNTs/ZLH-LP paste electrode was characterized by square wave voltammetry, electrochemical impedance spectroscopy, and cyclic voltammetry while the morphology properties of the MWCNTs, ZLH-LP, and MWCNTs/ZLH-LP were investigated using transmission electron microscopy and scanning electron microscopy. Under optimized conditions, the MWCNTs/ZLH-LP paste electrode demonstrated an excellent electrocatalytic activity towards oxidation of PCM in the linear responses’ ranges from 7.0 × 10−7 M to 1.0 × 10−4 M (correlation coefficient, 0.996) with the limit of detection obtained at 8.3 × 10−8 M. As a conclusion, the MWCNTs/ZLH-LP paste electrode revealed good repeatability, reproducibility, and stability, and was found to be applicable for use in pharmaceutical tablet samples. [Figure not available: see fulltext.]. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.
Nanotechnology Research Centre, Faculty of Science and Mathematics, Sultan Idris Education University, Tanjung Malim, 35900, Perak, Malaysia; Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, Tanjung Malim, 35900, Perak, Malaysia; Department of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Yogyakarta, Indonesia; Advanced Analytical Services Laboratory, MIMOS Bhd., Technology Park of Malaysia, Kuala Lumpur, 57000, Malaysia
