S. Atun, R. Arianingrum, L. Cahyaningsih, F.A. Pratiwi, R. Kusumaningrum, M. Khairuddean
Quercitrin is the main component that can be isolated from the parasitic plant Dendrophthoe falcata and exhibits high antioxidant activity. The purpose of this study is to make a quercitrin nanoemulsion formulation and test its antioxidant activity. This research method uses spontaneous emulsion. Quercitrin is formulated by spontaneous emulsion with the addition of oil, tween 80 as a surfactant, and phosphate buffer pH 7.0 as a water phase at low temperatures. Quercitrin nanoemulsion products are further characterized which include particle size, polydispersity index, zeta potential, physical properties, and stability. The antioxidant activity using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results showed that quercitrin nanoemulsion had an average particle size diameter of 10.2 to 36.5 nm, polydispersity index (PI) of less than 0.5, and zeta potential of-1.8 to-11.9 mV. Quercitrin nanoemulsion using virgine coconut oil (VCO) showed better stability than olive oil. The morphology of quercitrin nanoemulsion has the shape of a spherical particle. Quercitrin nanoemulsion is easily soluble in water and exhibits very high antioxidant activity like the original quercitrin. © RASĀYAN. All rights reserved.
Department of Chemistry Education, Faculty of Mathematic and Natural Science, Universitas Negeri Yogyakarta, Jl. Colombo No. 1 Depok, Sleman, Yogyakarta, 55281, Indonesia; School of Chemical Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia
