Paramita C. Kuswandi, Tutiek Rahayu
Obesity is a public health problem in the world. WHO estimates that 2.8 million people die from obesity and overweight. The prevalence of obesity in adults aged >18 years in Indonesia, especially in Yogyakarta has increased from 2007-2018. Genetic is one of the factors contributing to obesity and has been known to be related to obesity in families. The aim of this research was to analyze the inheritance pattern of obesity in families of young women in Yogyakarta. This study was an observational research with a cross sectional design and purposive sampling was also used as the sampling method. The participantss in this research were 36 obese young women aged 15-24 years with BMI ≥25 in Yogyakarta. BMI data of the young women families were also collected. BMI data from three generations of the participantss' families were obtained to analyze the inheritance pattern of obesity. This research was carried out from August 2020 - January 2021. Pedigree diagrams are used to analyze the obesity inheritance pattern based on BMI data from each families. Analysis was undertaken using hypothesis or assumptions for several modes of inheritance usually found for human traits. The results showed that the inheritance pattern of obesity in this research was 50% autosomal dominant and 44.44 % autosomal recessive. In conclusion, obesity in the families of young women in Yogyakarta follow an autosomal dominance and recessive inheritance pattern. © 2023 Author(s).
Department of Biology Education, Faculty of Mathematics and Natural Science, Universitas Negeri Yogyakarta, Indonesia
