Muhammad Iqbal Perdana, Ikhwan Yuda Kusuma, Wipsar Sunu Brams Dwandaru, Evy Yulianti, Barbara Tóth, Dezső Csupor, Miklós Takó, Csaba Vágvölgyi
Local management of bacterial infections is challenging. The antimicrobial effect of silver has long been recognized, but its use is limited due to its expensive nature and reduced applicability in liquids. This study aimed to synthesize chitosan-silver nanoparticles (CS-AgNPs) from reusable silver waste of the jewelry industry and investigate their antimicrobial properties against pathogenic microorganisms. X-Ray diffraction (XRD) analysis was used to confirm the crystalline structure of the recycled silver, with a strong diffraction peak observed at 2θ=38.60°. Agar disk diffusion showed inhibitory effects for CS-AgNPs on the growth of Escherichia coli, Staphylococcus aureus, and Candida albicans that depended on the concentration of AgNO3 solution used for preparation. In these tests, S. aureus was more susceptible to the treatment than E. coli and C. albicans. The CS-AgNP inhibited the growth of tested microorganisms with minimum inhibitory concentration (MIC50) values between 1.7 and 4.25 mg/mL. These findings highlight the potential of CS-AgNPs as effective antimicrobial agents. The use of waste materials in nanoparticle synthesis in this research offers a promising approach for sustainable and eco-friendly nanotechnology. © 2024 by the authors
Department of Biotechnology and Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, Szeged, H-6726, Hungary; Institute of Clinical Pharmacy, University of Szeged, Szikra utca 8, Szeged, H-6725, Hungary; Pharmacy Study Program, Universitas Harapan Bangsa, Banyumas, 53182, Indonesia; Physics Education Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta, Karangmalang Complex, Yogyakarta, 55281, Indonesia; Department of Biology Education, Faculty of Mathematics and Science, Universitas Negeri Yogyakarta, Yogyakarta, 55281, Indonesia
